Risk factors for carnitine deficiency in critically ill adults: A descriptive cross‐sectional study

Journal of Parenteral and Enteral Nutrition 2026 Open access

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Authors: Jennifer Gordon, Rebecca A. Brody, Hamed Samavat, Mireille Hamdan, Alexander L. Colonna, Jason Young, Laura D. Byham‐Gray
DOI: 10.1002/jpen.70044
Cited by: 1
References: 24

Abstract

BACKGROUND: Critical illness is a risk factor for carnitine deficiency. Carnitine deficiency may result in serious medical complications and poor clinical outcomes. This study aimed to identify the prevalence and potential predictors of carnitine deficiency. METHODS: This was a descriptive cross-sectional study conducted in a convenience sample of 144 critically ill adults admitted to a surgical or cardiovascular intensive care unit at the University of Utah Hospital, with serum carnitine levels measured from January 1, 2022, to December 31, 2024. Binary and multivariable logistic regression models were constructed to explore potential predictors of carnitine deficiency, which was defined as a free serum carnitine level

Fields of Study & Subjects

Metabolism and Genetic Disorders Clinical Nutrition and Gastroenterology Antibiotics Pharmacokinetics and Efficacy

Publication details

Journal / source
Journal of Parenteral and Enteral Nutrition
Publisher
Wiley
Volume
50
Issue
3
Pages
394–401
Publication date
7 January 2026
Language
EN