Menetrier's: A pediatric chronic state of disease with a possible heritable form

Menetrier's disease (MD) is a rare, typically transient, hypertrophic gastropathy with under 1000 adult cases and 50 pediatric cases known worldwide. Pediatric cases most often present with an infectious etiology. We present a case of a teenage male expressing a chronic state of disease without infectious origin. Menetrier's most typically causes protein loss and peripheral edema, however, this patient's only expression of disease is an enduring iron deficiency anemia. Moreover, seven additional paternal family members share the same diagnosis. This unique presentation and familial pattern of a very uncommon disease suggests a previously undescribed heritable form of MD. By recording such cases in the medical literature, we aim to boost providers ability to recognize this disease in all its known prior presentations.