Radiomics in Pancreatic Neuroendocrine Tumors (PNETs): Current Evidence, Reproducibility Gaps, and Research Directions

Journal of Surgical Oncology 2026

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Authors: Abdallah S. Attia, Sydney J Wellens, Kristen E. Limbach
DOI: 10.1002/jso.70177
Cited by: 1
References: 57

Abstract

Radiomics is a growing field for diagnosis, prognostication, and therapeutic decision-making in numerous solid tumors. Despite current promising findings in pancreatic neuroendocrine tumors (PNETs), significant limitations persist, including small cohorts, heterogeneous imaging protocols, and lack of external validation. This review elucidates the radiomics workflow, critically synthesizes the current evidence specifically surrounding the use of radiomics in PNETs, explicitly identifies methodological and reproducibility gaps, and outlines pragmatic research directions to bridge current drawbacks.

Fields of Study & Subjects

Neuroendocrine Tumor Research Advances Pancreatic and Hepatic Oncology Research Radiomics and Machine Learning in Medical Imaging

Publication details

Journal / source
Journal of Surgical Oncology
Publisher
Wiley
Volume
133
Issue
2
Pages
161–169
Publication date
12 January 2026
Language
EN