State of the Science: The epidemiology of posttraumatic stress disorder

Posttraumatic stress disorder (PTSD) is a mental health condition with widespread effects on mental and physical health and mortality. In this paper, we present the current state of research on the epidemiology of PTSD, including its prevalence, risk factors, and impact. The U.S. lifetime prevalence of PTSD is estimated to be 6.1%-8.3%, and the global prevalence is estimated at 3.9%. PTSD prevalence has been consistently found to be higher among certain subgroups, including women and military veterans. Risk factors for PTSD include pretrauma variables, preexisting mental health conditions, sociodemographic characteristics, and features of the traumatic event itself. Consequences of PTSD include effects on psychiatric comorbidity, physical health conditions, and all-cause and cause-specific mortality. Points of consideration and challenges affecting the study of PTSD epidemiology are noted, including debates on specifying a trauma criterion for diagnosis, the validity of complex PTSD as a diagnosis, and the dearth of recent population-based longitudinal data to understand this disorder. Suggestions for future research and clinical implications are discussed.