Wing‐Beating Tremor‐like Dyskinesia in a GBA1 Carrier
Abstract
CLINICAL PRACTICEand position-sensitive dystonic movements, bearing close resemblance with the "wing-beating" tremor reported in other dystonic syndromes.3 Notably, the parkinsonian tremor affecting his upper limbs in the OFF condition was phenomenologically very different and this might have been a clue to suspect a different pathophysiological mechanism, beyond the (missed) temporal pattern of occurrence with the Levodopa intakes.Accurate recognition of this rare phenomenology was crucial to ensure appropriate management.It is unknown whether his GBA1 status is related to this phenomenon.Atypical dyskinesia has been reported in GBA1 patients 4 but dystonia is not more frequent in GBA1 carriers than in other genetic forms of early-onset PD.
Fields of Study & Subjects
Lysosomal Storage Disorders Research
Neurological disorders and treatments
Parkinson's Disease Mechanisms and Treatments
Publication details
- Journal / source
- Movement Disorders Clinical Practice
- Volume
- 13
- Issue
- 8
- Pages
- 1995–1996
- Publication date
- 17 February 2026
- Language
- EN