LowCOST‐HSQC Variants for Fast‐Pulsing High ω 1 ‐Resolved 2D Experiments

Magnetic Resonance in Chemistry 2026 Open access

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Authors: David Schulze‐Sünninghausen, Johanna Becker, Martin R. M. Koos, Burkhard Luy
DOI: 10.1002/mrc.70102
Cited by: 1
References: 48

Abstract

ABSTRACT The LowCOST‐HSQC is a sensitivity‐enhanced HSQC version that retains unused proton polarization for subsequent scans in correlations to low natural abundance nuclei like C or N. Together with fast polarization distribution via isotropic mixing, it allows the acquisition of fast‐pulsing 2D experiments. We give a detailed introduction and comparison of three possible INEPT‐type transfer elements for the LowCOST approach—the original LowCOST, the ZIP, and a specific TIG‐BIRD element—and evaluate various variants of the LowCOST‐HSQC.

Fields of Study & Subjects

Nuclear physics research studies Advanced NMR Techniques and Applications Advanced Chemical Physics Studies

Publication details

Journal / source
Magnetic Resonance in Chemistry
Publisher
Wiley
Volume
64
Issue
7
Pages
655–665
Publication date
16 April 2026
Language
EN