Eight‐Year Progression of Clinical Practice Implementation Following Guideline Training in the EGUIDE Project

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Authors: Kenta Ide, Kazuhiko Yamamuro, Hisashi Yamada, Naomi Hasegawa, Yusuke Arai, Hiroyuki Muraoka, Toru Horinouchi, Yasushi Kawamata, Shinichiro Ochi, Takashi Tsuboi, Junya Matsumoto, Naoki Hashimoto
+7 more Kazutaka Ohi, Numata Shusuke, H. Hori, K. Inada, Koichiro Watanabe, Norio Yasui‐Furukori, Ryota Hashimoto
Cited by: 1
References: 24

Abstract

AIM: Clinical practice guidelines have improved the quality and standardization of psychiatric care; however, their long-term implementation in real-world settings remains limited. The Effectiveness of the Guidelines for Dissemination and Education (EGUIDE) project was established to promote sustained evidence-based practice through a multilayered educational program for psychiatrists in Japan. METHODS: This multicenter observational study longitudinally tracked psychiatrists' self-rated clinical behavior (CB) scores related to guideline adherence for up to 8 years after initial EGUIDE participation. CB was assessed using a validated questionnaire covering general guideline use (CB-G), schizophrenia (CB-S), and major depressive disorder (CB-D), with a comprehensive index (CB-C) representing the mean of all domains. Data were analyzed using the Kruskal-Wallis test, the Mann-Whitney U test, and the Bonferroni correction (two-tailed p < 0.05). RESULTS: ), with small-to-moderate effect sizes (r = 0.09-0.29). These improvements were maintained throughout the 8-year follow-up, with no significant decline, and several domains showed small but continued increases between 3 and 7 years post training. CONCLUSION: The EGUIDE program achieved long-term, sustained improvements in psychiatrists' guideline-adherent clinical behaviors through an integrated system combining education, supervision, feedback, and follow-up. This autonomous, cyclical framework represents a high-impact model for continuous quality improvement and may be adaptable to other medical specialties.

Fields of Study & Subjects

Clinical practice guidelines implementation Health Policy Implementation Science Health Sciences Research and Education

Publication details

Journal / source
Neuropsychopharmacology Reports
Publisher
Wiley
Volume
46
Issue
1
Pages
e70095–e70095
Publication date
1 March 2026
Language
EN