The Sign of Leser–Trélat as a Possible Indicator of Prostate Adenocarcinoma: A Case Report
Abstract
BACKGROUNDS: The sign of Leser-Trélat (SLT) is defined by the abrupt onset of multiple pruritic or nonpruritic seborrhoeic keratoses (SKs) over a short interval, predominantly affecting the back, and is most frequently associated with internal malignant neoplasia, particularly gastric and colorectal adenocarcinoma. CASE PRESENTATION: We report a rare case of a 65-year-old male with SLT in association with prostate adenocarcinoma. CONCLUSIONS: This report underscores the importance of including prostate assessment in the diagnostic work-up of men with rapidly evolving, multiple, and progressive SKs.
Fields of Study & Subjects
Skin Diseases and Diabetes
Genetic and rare skin diseases.
Cancer and Skin Lesions
Publication details
- Journal / source
- The Prostate
- Publisher
- Wiley
- Volume
- 86
- Issue
- 6
- Pages
- 732–734
- Publication date
- 29 January 2026
- Language
- EN