Male Sex Is Associated With Severe Pulmonary Hypertension and Worse Outcome in Chronic Obstructive Pulmonary Disease Patients Referred for Right Heart Catheterization

Pulmonary Circulation 2026 Open access

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Authors: Katarina Zeder, Klemens Orasche, Teresa John, Philipp Douschan, Vasile Foris, Shelsey W. Johnson, Bradley A. Maron, Nikolaus Kneidinger, Gabor Thomas Kovacs
DOI: 10.1002/pul2.70233
Cited by: 1
References: 14

Abstract

Sex differences in COPD patients with concomitant pulmonary hypertension remain unexplored. Analyzing 171 patients from the GRAPHIC registry in Graz, Austria, we found that male sex was independently associated with increased mortality risk, despite comparable comorbidities and airflow obstruction, which may be explained by the increased rate of severe PH.

Fields of Study & Subjects

Pulmonary Hypertension Research and Treatments Chronic Obstructive Pulmonary Disease (COPD) Research Venous Thromboembolism Diagnosis and Management

Publication details

Journal / source
Pulmonary Circulation
Publisher
Wiley
Volume
16
Issue
2
Pages
e70233–e70233
Publication date
31 March 2026
Language
EN