Colorimetric and Photothermal Hollow Nanocomposite Based on Silver‐Seeded Prussian Blue Analog for Dopamine Monitoring and Photothermal Sterilization

ABSTRACT Multi‐element Prussian blue analog (PBA) nanocomposites have attracted wide attention for their superior characteristics to single‐functional nanomaterials in extensive applications of diagnosis and therapy. In this study, a novel hollow nanocomposite was designed and fabricated by embedding S 2− and Ag nanoparticles into a NiCuMnFe (PBA). The introduction S 2− and Ag nanoparticles greatly enhanced the catalytic and photothermal performance of multi‐element NiCuMnFe PBA. Based on its versatility of outstanding performance, a rapid and sensitive colorimetric detection platform for dopamine (DA), with a limit of detection (LOD) of 0.567 μM was constructed, and an efficient antibacterial nanoplatform was obtained with highly effective antibacterial performance (100% inhibition rate of bacteria under optimal conditions). This work provides a feasible reference for the reasonable design of multifunctional nanocomposites in biosensor and medical treatment applications.