Copper‐Catalyzed Three‐Component Sulfenylation of Imidazopyridines with Ethyl Potassium Xanthogenate and Aryl Halides
Abstract
ABSTRACT This work demonstrates a copper‐catalyzed three‐component sulfenylation transformation of imidazopyridines at the C‐3 position. Xanthogenate was explored as a thiol surrogate in this reaction owing to its merits. Over 30 diversely substituted products incorporating various functional groups were synthesized in moderate to good yields. Notably, this method features operational simplicity, avoids complex catalytic systems, and has been successfully scaled up to the gram level without compromise in efficiency.
Fields of Study & Subjects
Sulfur-Based Synthesis Techniques
Catalytic C–H Functionalization Methods
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- ChemistrySelect
- Volume
- 11
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN