Epoxide‐Based Ring‐Opening–Ring‐Closing Strategy Towards Oxygen‐Containing Heterocyclic Scaffolds
Abstract
ABSTRACT This review systematically describes a decade update on the synthetic utility of strained epoxide and various methodologies used for the synthesis of five‐, six‐, and seven‐membered rings with emphasis on CO 2 fixation and atom‐economic ring expansion. Stereoselective ring‐opening reactions of epoxides disclose new and efficient routes for synthetically and pharmaceutically potent oxygen‐containing heterocyclic structures as well as acyclic scaffolds.
Fields of Study & Subjects
Carbon dioxide utilization in catalysis
Synthesis and Catalytic Reactions
Oxidative Organic Chemistry Reactions
Publication details
- Journal / source
- ChemistrySelect
- Publisher
- Wiley
- Volume
- 11
- Issue
- 2
- Publication date
- 1 January 2026
- Language
- EN