Synthesis of Benzo[4,5]Thiazolo[3,2‐ a ]Pyridine Derivatives via NHC‐Catalyzed [3+3] Annulation of δ ‐Acetoxy Allenoates
Abstract
ABSTRACT An N ‐heterocyclic carbene (NHC)‐catalyzed [3+3] annulation of δ ‐acetoxy allenoates with 2‐acylbenzothiazoles has been developed. This dearomative annulation methodology provided a facile method for the synthesis of benzo[4,5]thiazolo[3,2‐ a ]pyridine derivatives with a broad substrate scope in moderate to good yields (24 examples, up to 74% yield).
Fields of Study & Subjects
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Synthesis and Reactivity of Heterocycles
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- ChemistrySelect
- Volume
- 11
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN