Anti‐Swelling and Thermally‐Actuated Adhesive Dual‐Network Hydrogel for Annulus Fibrosus Repair With Self‐Healing Capability

Small 2026

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Authors: Qiangwang Geng, Haoran Zhang, Tao Guo, Yiwei Zhao, Jianguo Zhang, 张风华, Shengru Wang, Jinsong Leng
DOI: 10.1002/smll.74894
Cited by: 1
References: 27

Abstract

To prevent nucleus pulposus reherniation following annulus fibrosus (AF) rupture, effective defect sealing is imperative post-discectomy. Ideal repair materials require excellent cytocompatibility, tailored adhesion, and long-term stability. Herein, a double-network hydrogel (PNG) featuring a dense hydrogen-bonded network is engineered by integrating gelatin with poly(acrylic acid-co-N-acryloyl glycinamide) via a pH-controllable crosslinking strategy. PNG exhibits exceptional dimensional stability (swelling ratio

Fields of Study & Subjects

Spine and Intervertebral Disc Pathology Surgical Sutures and Adhesives Tendon Structure and Treatment

Publication details

Journal / source
Small
Publisher
Wiley
Volume
22
Issue
55
Pages
e74894–e74894
Publication date
29 July 2026
Language
EN