Multicomponent Reaction Strategies for the Synthesis of 4‐(Indol‐3‐Yl)‐4 H ‐Chromene Derivatives: Recent Developments

The Chemical Record 2026

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Authors: Elizabeth J. Diana, Jisna Jose, Thomas Mathew
DOI: 10.1002/tcr.202500166
Cited by: 1
References: 39

Abstract

This review highlights recent advancements (2021-2025) in the synthesis of 4-(indol-3-yl)-4H-chromene derivatives, a promising class of compounds with diverse biological activities, including anticancer, antifungal, antitumor, anti-HIV, and antioxidant properties. The focus is on multicomponent reactions (MCRs) as a valuable tool for efficient synthesis, offering benefits such as environmental sustainability and precise targeting. The review explores MCR strategies and substrate scope, shedding light on their potential therapeutic applications.

Fields of Study & Subjects

Multicomponent Synthesis of Heterocycles Synthesis of Indole Derivatives Synthesis and bioactivity of alkaloids

Publication details

Journal / source
The Chemical Record
Publisher
Wiley
Volume
26
Issue
4
Pages
e202500166–e202500166
Publication date
28 January 2026
Language
EN