Designing Tailored Molecular Cavities Using Calix[5]arenes as Building Blocks
Abstract
This study examines the shapes and dimensions of cavities defined by well-designed molecular structures. We discuss our work on creating custom cavities using calix[5]arenes. The shapes and dimensions of these cavities are precisely determined to selectively interact with specific guest molecules. We demonstrate that strategic design leads to strong binding, guest selectivity, and responsiveness to stimuli. These results highlight the importance of cavity customization in advancing host-guest systems for potential applications in molecular recognition and supramolecular materials.
Fields of Study & Subjects
Supramolecular Chemistry and Complexes
Supramolecular Self-Assembly in Materials
Crystallography and molecular interactions
Publication details
- Journal / source
- The Chemical Record
- Publisher
- Wiley
- Volume
- 26
- Issue
- 6
- Pages
- e202500281–e202500281
- Publication date
- 26 March 2026
- Language
- EN