Squamous cell carcinoma of the vulva in a dog

Abstract This report describes the diagnosis and treatment of a squamous cell carcinoma of the vulva in a bitch. An 11‐year‐old female, neutered large crossbreed, presented to the primary practitioner for investigation of a slow‐growing vulval mass. Cytology was suggestive of a squamous cell carcinoma, and the bitch was referred. Staging did not reveal any evidence of metastasis and was followed by a complete vulvectomy. Marginal excision was achieved, and histopathology confirmed a squamous cell carcinoma affecting the vulva. Immunohistochemistry did not support the presence of canine papillomavirus infection. Eight months postoperatively, the dog re‐presented with recurrence of the squamous cell carcinoma. Electrochemotherapy was performed, which achieved partial resolution. Six months after the final electrochemotherapy session, the owners reported the dog remained clinically well, with no complications associated with treatment. To the best of the authors’ knowledge, this is the first report describing the diagnosis and treatment of squamous cell carcinoma of the vulva in a dog.