Postpunktionskopfschmerz

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Authors: Philipp Helmer, Benedikt Hermann Siegler, Lena Reese, Patrick Meybohm, Peter Kranke, Vanessa Neef
Cited by: 1
References: 45

Abstract

Post-dural puncture headache (PDPH) is a frequent yet often underestimated complication of neuraxial anesthesia. The presumed mechanism involves cerebrospinal fluid loss due to accidental dural perforation, leading to intracranial hypotension and a secondary compensatory vasodilation. Meningeal irritation and neuroinflammatory processes also contribute to the complex pathophysiology. The main symptom is a severe orthostatic headache with pain exacerbation in an upright posture. This can be accompanied by neck stiffness, tinnitus, visual and other neurological disorders. Patient-specific risk factors are young age, female sex and a positive history of headaches and anesthesia-related factors include puncture needle size and design. The epidural blood patch (EBP) is the current gold standard for treatment. The occasionally considerable patient suffering and optimization of the outcomes necessitate a critical analysis of the treatment options.

Fields of Study & Subjects

Anesthesia and Pain Management Neurosurgical Procedures and Complications Intraoperative Neuromonitoring and Anesthetic Effects

Publication details

Journal / source
Die Anaesthesiologie
Publisher
Springer Science and Business Media LLC
Volume
75
Issue
1
Pages
67–79
Publication date
1 January 2026
Language
DE