Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Intensive Care Medicine 2026 Open access

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Authors: Hallie C. Prescott, Massimo Antonelli, Waleed Alhazzanic, Morten Hylander Møller, Fayez Alshamsi, Luciano C. P. Azevedo, E Belley-Cote, Jan De Waele, Lennie Derde, Joanna C. Dionnec, L.E. Evans, Hayley B. Gershengorn
+57 more Carol L. Hodgson, Kimia Honarmandc, Jozef Kesecioğlu, Lauralyn McIntyre, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Bram Rochwergc, Olurotimi Akinola, Kwame Akuamoah-Boateng, Laura Alberto, D Angus, Yassen Arabi, E. Azoulay, Maurizio Cecconi, Pauline Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, R. Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P. Hale, Naomi Hammond, Madiha Hashmi, L. Heunks, Theodore J. Iwashyna, Shevin T. Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D. Lejnieks, Mitchell M. Levy, Flavia R. Machado, M. D. Maia, Henry Masur, Ryan C. Maves, Steven McGloughlin, J. McPeake, Nicholas M. Mohr, Sheila Nainan Myatra, Marlies Ostermann, S. Peake, M W Pletz, Jay Roberts, Regis G. Rosa, Robert Sawyer, Christa Schorr, Steven Q. Simpson, Li Weng, W. Joost Wiersinga, A Rhodes, Craig M. Coopersmith
DOI: 10.1007/s00134-026-08361-1
Cited by: 50
References: 590

Abstract

Sepsis, life-threatening acute organ dysfunction due to infection [ 1 ], is a global health priority [ 2 , 3 ] with approximately 49 million cases and 13 million sepsis-related deaths each year [ 4 , 5 , 6 ]. Beyond being acutely deadly, sepsis contributes to new and worsened physical, cognitive, and mental health problems in many survivors [ 7 , 8 ]. Early identification and treatment are critical to improving outcomes.

Fields of Study & Subjects

Sepsis Diagnosis and Treatment Nosocomial Infections in ICU Immune Response and Inflammation

Publication details

Journal / source
Intensive Care Medicine
Publisher
Springer Science and Business Media LLC
Volume
52
Issue
5
Pages
863–936
Publication date
23 March 2026
Language
EN