Atorvastatin regulates hepatic transcriptome PXR dependently but distinct from pregnenolone 16α-carbonitrile and does not induce PXR-mediated liver steatosis

Archives of Toxicology 2026

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Authors: Heba Nabil, Mahmoud‐Sobhy Elkhwanky, Mohamed Hassanen, Einari A. Niskanen, Raghavendra Mysore, Jorma J. Palvimo, Outi Kummu, Jukka Hakkola
DOI: 10.1007/s00204-025-04280-0
Cited by: 0
References: 53

Fields of Study & Subjects

Drug-Induced Hepatotoxicity and Protection Peroxisome Proliferator-Activated Receptors Liver Disease Diagnosis and Treatment

Publication details

Journal / source
Archives of Toxicology
Volume
100
Issue
4
Pages
1443–1463
Publication date
14 January 2026
Language
EN