Modulation of AMPK/SIRT1 signaling by piribedil attenuates cyclophosphamide-induced nephrotoxicity via PI3K/Akt, MAPKs, and TLR4/NLRP3 pathways with regulation of KIM-1/NGAL

Naunyn-Schmiedeberg s Archives of Pharmacology 2026

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Authors: Ahmed M. El-Dessouki, Tarek A. Yousef, Mashael A. Alghamdi, Arwa Omar Al Khatib, Bassant M. Barakat, Asmaa Ramadan, Nada A. Ashour, Sahar K. Ali, Mohamed N. Goda, Ahmed A. Al-Karmalawy
DOI: 10.1007/s00210-025-04909-y
Cited by: 2
References: 76

Fields of Study & Subjects

Chemotherapy-induced organ toxicity mitigation Sirtuins and Resveratrol in Medicine Drug-Induced Hepatotoxicity and Protection

Publication details

Journal / source
Naunyn-Schmiedeberg s Archives of Pharmacology
Publisher
Springer Science and Business Media LLC
Volume
399
Issue
7
Pages
10353–10372
Publication date
3 February 2026
Language
EN