Chemical cleavage coupled with LCMS to report on the true diastereomeric distributions of phosphorothioate linkages in gapmer ASO

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Authors: Zifan Li, Tai Nguyen, Xuan Zhou, Li Xiao, George M. Bou-Assaf
Cited by: 1
References: 45

Fields of Study & Subjects

DNA and Nucleic Acid Chemistry Origins and Evolution of Life Advanced biosensing and bioanalysis techniques

Publication details

Journal / source
Analytical and Bioanalytical Chemistry
Publisher
Springer Science and Business Media LLC
Volume
418
Issue
8
Pages
2415–2425
Publication date
11 February 2026
Language
EN