Lumbar spine DXA T-score and QCT BMD cutpoint values for defining osteofrailia among older men: a framework for further refinement

Skeletal Radiology 2026 Open access

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Authors: Y. X. J. Wáng, Timothy C Y Kwok, Maria Pilar Aparisi Gómez, Ben-Heng Xiao, Jason C S Leung, Fernando Ruiz Santiago, Wing P. Chan; Guo-Shu Huang; Shu-Mei Hsu; Yue-Cune Chang; Wei-Pin Ho;, Daniele Diacinti, Ali Guermazi, Alberto Bazzocchi
DOI: 10.1007/s00256-026-05133-2
Cited by: 4
References: 56

Abstract

Older men suffer from hip FFx (fragility fracture) at femoral neck T-score approximately 0.6 higher than older women, thus we proposed a new category of low BMD status, osteofrailia, for older Caucasian men with femoral neck T-score ≤ -2.0 (T-score ≤ -2.1 for older East Asian men) who have an increased risk of hip FFx. Around the age of 78 years, mean LS (lumbar spine) QCT BMD is around 68 mg/mL and 100 mg/mL for East Asian men and Caucasian men, respectively. For East Asian men, LS QCT BMD

Fields of Study & Subjects

Bone health and osteoporosis research Spine and Intervertebral Disc Pathology Hip and Femur Fractures

Publication details

Journal / source
Skeletal Radiology
Publisher
Springer Science and Business Media LLC
Volume
55
Issue
5
Pages
915–929
Publication date
23 January 2026
Language
EN