Global bibliometric analysis of comorbid depression and anxiety in inflammatory bowel disease (2010–2024)

BACKGROUND: Inflammatory bowel disease (IBD) is an intestinal inflammatory disease of unknown etiology. Depression and anxiety are prevalent mental symptoms associated with IBD. Although numerous studies have explored the potential relationship between IBD and these psychological conditions, a bibliometric analysis on this topic has yet to be conducted. METHODS: We screened 420 relevant articles from the Web of Science Core Collection (WoSCC) database from 2010 to 2024 and analyzed them using software such as CiteSpace, VOSviewer, Pajek, and Tableau. RESULTS: The USA (98 papers), the University of Manitoba (24 papers), Inflammatory Bowel Diseases (56 papers), and Charles N. Bernstein (20 papers) were the most productive country, institution, journal, and author, respectively. High-frequency keywords in this field include "quality-of-life," "symptoms," "prevalence," "comorbidity," "association," "therapy," and "management." Additionally, emerging research frontiers encompass topics such as "mouse model," "remission," "disorder," and "gut microbiota." CONCLUSIONS: Over the past 14 years, there has been a notable increase in research focused on depression and anxiety associated with inflammatory bowel disease. Key areas such as "mouse models," "remission," "disorder," and "gut microbiota" are poised to become focal points of future investigations. These findings may offer new avenues for researchers to explore.