Trihaloisocyanuric acids: useful reagents for oxidative cyclization of diols to lactones

Monatshefte für Chemie - Chemical Monthly 2026 Open access

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Authors: Carlos Vinícius P. dos Santos, Raphael C. Alves, Marcio C. S. de Mattos
DOI: 10.1007/s00706-026-03432-x
Cited by: 1
References: 48

Abstract

Abstract A novel and convenient procedure for the oxidative cyclization of diols to the corresponding lactones was achieved using trichloro- and tribromoisocyanuric acids. The methodology provided 5–11-membered lactones in 50–98% yield under simple and mild conditions. A reaction pathway is proposed by experimental evidence and DFT calculations at M062x/6-311G(d,p) level. Graphical abstract

Fields of Study & Subjects

Vanadium and Halogenation Chemistry Oxidative Organic Chemistry Reactions Catalytic C–H Functionalization Methods

Publication details

Journal / source
Monatshefte für Chemie - Chemical Monthly
Publisher
Springer Science and Business Media LLC
Volume
157
Issue
2
Pages
271–280
Publication date
27 January 2026
Language
EN