Delayed recovery following myasthenic exacerbation and subsequent endplate-protecting treatment
Abstract
Endplate-protecting therapies have improved treatment of myasthenia gravis and indicate a rapid onset of their treatment effect. Currently, these substances can be used following myasthenic exacerbation (ME). Clinical worsening due to ME however often results in prolonged recovery. We here evaluated the treatment courses of patients having received endplate-protecting treatment following ME. Among 12 patients with ME described here, seven received endplate-protecting therapies. Our findings indicate that acceptable recovery usually takes nine months. In the lights of recent trials for treatment of myasthenia, our findings implicate that the effectiveness of novel substances should be judged only after sufficient observation periods.
Fields of Study & Subjects
Myasthenia Gravis and Thymoma
Peripheral Neuropathies and Disorders
Neurogenetic and Muscular Disorders Research
Publication details
- Journal / source
- Neurological Sciences
- Volume
- 47
- Issue
- 2
- Pages
- 227–227
- Publication date
- 1 February 2026
- Language
- EN