Clinical practice guideline for pediatric IgA vasculitis in Japan 2023: a digest-secondary publication

IgA vasculitis (IgAV) is a common childhood vasculitis characterized by three key symptoms: skin, joint, and abdominal symptoms. This disease is frequently encountered in general pediatric practice. Approximately 30% of IgAV cases develop IgAV nephritis (IgAVN). It is a significant complication that determines the long-term prognosis of the patients. Severe IgAVN cases require evaluation through renal biopsy, and the condition’s severity is important for determining the subsequent treatment strategies. However, Japan currently has no clinical guidelines for pediatric IgAV. In response to a request for their creation, the Japanese Society of Pediatric Nephrology collaborated with the Japanese Society of Nephrology, the Japanese Society of Pediatric Rheumatology, the Japanese Society of Pediatric Gastroenterology and Hepatology, the Japanese Society of Pediatric Dermatology, and the Japanese Society of Dermatological Histopathology to develop these guidelines, which are Japan’s first clinical guidelines for pediatric IgAV, to clarify the basic treatment strategies based on accumulated evidence and to support the provision of high-quality, evidence-based medical care throughout Japan. This article provides a digest version of the 2023 Clinical Guidelines for Pediatric IgAV (in Japanese) (Shindan To Chiryo Sha, Inc., Tokyo, Japan) as a secondary publication in English, with a focus on key points [ 1 , 2 ].Please verify if the provided city and country are correct and amend if necessary.We corrected the postal number of the Kansai Medical University.