Mitral annular disjunction and mitral valve prolapse: echocardiographic-MRI insights into cardiac function

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Authors: Max D. King, Andrew C. Peters, Stuart Karimi, Alyson N. Owen, Baskaran Sundaram, Behzad B. Pavri
Cited by: 1
References: 21

Abstract

BACKGROUND: Mitral annular disjunction (MAD) may accompany mitral valve prolapse (MVP) and is linked to ventricular arrhythmias. Its impact on global cardiac performance (specifically cardiac index (CI) and output (CO)), remains incompletely defined. Cardiac MRI (CMR) allows precise measurement of MAD, assessment of mitral annular dynamics, and detection of myocardial fibrosis via late gadolinium enhancement (LGE). We investigated both CMR and TTE metrics in patients with varying degrees of MAD compared to MVP-only. METHODS AND RESULTS: Fifty-six patients who underwent CMR and TTE (mean age 61, 33 female) were divided into MAD ≥2 mm and MVP (the "MAD + MVP" group, n = 41) or MVP-only (n = 15). MAD was classified as

Fields of Study & Subjects

Cardiovascular Function and Risk Factors Cardiac Imaging and Diagnostics Cardiac Valve Diseases and Treatments

Publication details

Journal / source
The International Journal of Cardiovascular Imaging
Publisher
Springer Science and Business Media LLC
Volume
42
Issue
8
Pages
1591–1600
Publication date
27 April 2026
Language
EN