A first-in-human phase 1a study of LP-184, a tumor-site activated novel alkylating agent, in patients with advanced solid tumors

Investigational New Drugs 2026

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Authors: Daruka Mahadevan, Jay Parekh, Joseph T. Beck, Willam B. McKean, Karisa C. Schreck, Anthony J. Olszanski, Misty D. Shields, Vu Phan, John T. Hamm, Bruce B. Bank, Jianli Zhou, Marc Chamberlain
+2 more Kishor Bhatia, Reginald Ewesuedo
DOI: 10.1007/s10637-026-01626-y
Cited by: 1
References: 19

Fields of Study & Subjects

Cancer Hypoxia and Metabolism Histone Deacetylase Inhibitors Research Nanoparticle-Based Drug Delivery

Publication details

Journal / source
Investigational New Drugs
Publisher
Springer Science and Business Media LLC
Publication date
7 July 2026
Language
EN