Dosimetry studies on amino acids using diffuse reflectance measurements for high doses

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Authors: Sandip Mondal, S. H. Shinde, Sneha Chandrasekhar, Probal Chaudhury
Cited by: 1
References: 9

Abstract

This study investigates alanine, glycine, and glutamine as high-dose gamma radiation dosimeters using diffuse reflectance spectroscopy (DRS). DRS provides a non-invasive, cost-effective method for rapid dose estimation. Amino acid powders were irradiated from 0.1 to 100 kGy, and their reflectance spectra in the range of 300 to 510 nm, were analysed. Non-linear dose–response curves were observed, with alanine, glycine, and glutamine showing peak sensitivities at different dose ranges. Measurements were within ± 6.3% suggesting good reproducibility, stability over time and temperature, and unaffected by dose fractionation. These results highlight amino acids' potential for reliable, long-term radiation dosimetry in routine monitoring applications.

Fields of Study & Subjects

Radiation Effects and Dosimetry Advanced Radiotherapy Techniques Radioactive contamination and transfer

Publication details

Journal / source
Journal of Radioanalytical and Nuclear Chemistry
Publisher
Springer Science and Business Media LLC
Volume
335
Issue
1
Pages
375–384
Publication date
1 January 2026
Language
EN
Document type
Book chapter