Magnetic enhancement of Fe3O4 nanoparticles through dual surface modification against biofilm formation
Abstract
Biofilm formation enhances bacterial resistance, posing major challenges in infection control. This study developed biocompatible magnetite (Fe₃O₄) nanoparticles with improved antibiofilm activity. Fe₃O₄ nanoparticles were synthesized via a hydrothermal method and functionalized with gum Arabic (GA) and folic acid (FA). XRD confirmed a pure cubic spinel structure, while FTIR verified successful surface modification. FESEM revealed quasi-spherical, well-dispersed particles, and UV–Vis analysis showed slight shifts in optical absorption after functionalization. VSM results indicated soft magnetic behavior, with increased saturation magnetization in FA-coated samples and a slight reduction in GA-coated ones. Hemolysis assays confirmed good biocompatibility (
Fields of Study & Subjects
Advanced Nanomaterials in Catalysis
Nanoparticles: synthesis and applications
Nanoparticle-Based Drug Delivery
Publication details
- Journal / source
- Journal of Sol-Gel Science and Technology
- Publisher
- Springer Science and Business Media LLC
- Volume
- 117
- Issue
- 3
- Publication date
- 4 March 2026
- Language
- EN