Fifteen years on: a review of the Cam-CAN study of the cognitive neuroscience of ageing

The Cambridge Centre for Ageing and Neuroscience (Cam-CAN, www.cam-can.org ) was established 15 years ago to investigate the cognitive and brain bases of healthy adult ageing. Demographic, health and lifestyle data, cognitive data and a wide range of brain imaging data, were shared with other researchers around the world, resulting in many scientific findings. Here we review these findings under the broad headings of 'neuroscience of ageing', 'methodological developments' and 'clinical/translational use', and look to future longitudinal continuation and sharing of further data.