The effects of prediabetes and type 2 diabetes mellitus on cognitive status, physical function, and fatigue in older adults: a case-control study

OBJECTIVE: The purpose of this study was to compare the cognitive status, physical function, and fatigue levels of Type-2 Diabetes Mellitus (T2DM), prediabetes, and healthy older adults. METHODS: Volunteers aged 60 and over were included in the study. Participants divided into four groups according to hemoglobin A1c (HbA1c) levels: healthy, prediabetes, controlled T2DM, and uncontrolled T2DM. Cognitive function, spatial ability, functional mobility with and without dual-task conditions, reaction time, fatigue, and biochemical parameters were evaluated. RESULTS: A total of 94 participants (53 female, 41 male, mean age:67.12±5.84 years) were included. Significant group differences were observed in attention and delayed recall subdomains and total Montreal Cognitive Assesment scores (p