A case of gastric neuroendocrine tumor with an unusual morphology

Clinical Journal of Gastroenterology 2026 Open access

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Authors: Takuya Ohashi, Kenichiro Okimoto, Keisuke Matsusaka, Tomoaki Matsumura, Tsubasa Ishikawa, Hirotaka Oura, Tatsuya Kaneko, Yuki Ohta, Takasi Taida, Jun Kato
DOI: 10.1007/s12328-026-02289-1
Cited by: 0
References: 7

Abstract

Gastric neuroendocrine tumors (NETs), derived from enterochromaffin-like cells, commonly exhibit submucosal extension and manifest as submucosal tumor (SMT)-like lesions during endoscopy. We report a rare case of a gastric NET with endoscopical unusual pedunculated and reddish morphology. A 15-mm lesion in the gastric body showed histologically proved to be a grade G2 NET. Endoscopic submucosal dissection was performed, followed by surgery due to lymphatic invasion. Histological examination of the background gastric mucosa in the resected specimen revealed features of autoimmune gastritis, consistent with a type 1 gastric NET according to the Rindi classification. Recognition of such atypical morphology may aid diagnosis.

Fields of Study & Subjects

Neuroendocrine Tumor Research Advances Gastrointestinal Tumor Research and Treatment Gastric Cancer Management and Outcomes

Publication details

Journal / source
Clinical Journal of Gastroenterology
Volume
19
Issue
2
Pages
446–450
Publication date
16 February 2026
Language
EN