Change in the prognostic utility of regional left ventricular longitudinal strain values in patients undergoing transcatheter aortic valve implantation

BACKGROUND: To evaluate the difference in prognostic utility of echocardiographic parameters between pre- and post-transcatheter aortic valve implantation (TAVI) periods. METHODS AND RESULTS: This study enrolled 189 patients who underwent TAVI at Kumamoto University Hospital between 2015 and 2023 and had available echocardiographic data for the pre- and post-TAVI periods. Thirty-seven deaths occurred within the follow-up period (median 574 [357-934] days after post-TAVI period). Apical longitudinal strain (LS) in the pre- and post-TAVI periods and mid LS in the post-TAVI period were significantly associated with all-cause death after adjusting for various factors (pre-TAVI apical LS, hazard ratio [HR] 0.92, 95% confidence interval [CI] 0.85-0.99, p