An unusual occurrence of a huge ovarian fibroma in a postmenopausal woman impersonating ovarian malignancy: a case report

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Authors: Aparna Jarathi, Naina Kumar, Annapurna Srirambhatla, Ayya Syama Sundar, Ashutosh Rath
Cited by: 0
References: 16

Abstract

To report the elusive presentation of a huge ovarian fibroma in a postmenopausal woman, the role of Magnetic Resonance Imaging (MRI) in its evaluation and final diagnosis, with the histopathological examination. A 50-year-old postmenopausal woman presented with a large right ovarian tumour, ascites, and high levels of CA-125. On MRI, the lesion appeared solid to cystic, exhibiting heterogeneous, hypointense-hyperintense signal, with diffusion restriction in the solid component of the mass in diffusion-weighted magnetic resonance (MR) images. A definitive diagnosis of right ovarian fibroma was reached after the histological analysis revealed fascicles and sheets of spindle cells within a collagenized stroma. This case report highlights the atypical and deceptive presentation of ovarian fibroma, emphasizing the challenges in clinical and imaging-based diagnosis.

Fields of Study & Subjects

Ovarian cancer diagnosis and treatment Uterine Myomas and Treatments Breast Lesions and Carcinomas

Publication details

Journal / source
Discover Medicine
Volume
3
Issue
1
Publication date
12 February 2026
Language
EN