Recent advances in the synthesis of furo[2,3-b]pyridine derivatives through novel domino annulations

Furo[2,3- b ]pyridines have garnered great interest owning to their broad applicability in pharmaceutical design and materials science. Consequently, the development of efficient and practical routes to access furo[2,3- b ]pyridine derivatives is a topic of significance in both medicinal chemistry and materials research. Among the diverse synthetic strategies, domino annulation reactions have emerged as particularly powerful methodologies, enabling the one-step assembly of diverse cyclic architectures. In recent years, notable progress has been achieved in the synthesis of furo[2,3- b ]pyridine derivatives through domino annulations. This review summarizes the advances in this field since 2014, offering a concise overview of key developments.