Quantum biosensors and organ-on-a-chip systems: a converging frontier for real-time biomedical insight
Abstract
The convergence of quantum sensing and organ-on-a-chip (OoC) technologies represents an untapped frontier in biomedical diagnostics and personalised medicine. This Perspective argues that quantum biosensors such as nitrogen-vacancy (NV) centres in diamond and quantum dots offer transformative capabilities for in situ, real-time monitoring within physiologically relevant microfluidic platforms. We outline the conceptual framework for integrating these technologies, highlight emerging proof-of-concept demonstrations, and identify the engineering, biological, and translational hurdles that must be overcome. We propose a roadmap toward hybrid quantum OoC systems capable of redefining preclinical testing, adaptive therapeutics, and systems biology.
Fields of Study & Subjects
Diamond and Carbon-based Materials Research
3D Printing in Biomedical Research
Analytical Chemistry and Sensors
Publication details
- Journal / source
- Discover Sensors
- Publisher
- Springer Science and Business Media LLC
- Volume
- 2
- Issue
- 1
- Publication date
- 8 February 2026
- Language
- EN