SPARC: A programmable molecular diagnostic platform based on a signal-triggered, self-supplied crRNA and tiered PER-transcription-CRISPR cascade for early detection of hepatocellular carcinoma

Analytica Chimica Acta 2026

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Authors: Xinying Chang, Cong Han, Haishuo Ji, Zhe Zeng, Jangsik Yang, Qirui Liu, Chao Jia, Lili Zhao, Chunlei Zhou, Shujia Chen, Wolfgang Knoll, J Li
+2 more Zhenglu Wang, Liyun Zhang
DOI: 10.1016/j.aca.2026.345209
Cited by: 1
References: 32

Fields of Study & Subjects

Advanced biosensing and bioanalysis techniques MicroRNA in disease regulation RNA Interference and Gene Delivery

Publication details

Journal / source
Analytica Chimica Acta
Publisher
Elsevier BV
Volume
1394
Pages
345209–345209
Publication date
10 February 2026
Language
EN