Constructive Appraisal of “Real-World Study Assessing Sensitivity and Clinical Utility of a Host-Protein Test in Adult Emergency Department Patients With Blood Culture Ordered”
Abstract
We read with interest the recent study by LoVerde et al1 evaluating the diagnostic performance and clinical utility of the MeMed BV host-protein test in adult emergency department patients with suspected infection. The authors demonstrated impressive sensitivity (96.4%) and negative predictive value (98.6%) for distinguishing bacterial from viral infections and reported improved antibiotic alignment over time. Although this real-world investigation contributes meaningfully to diagnostic stewardship, several methodological and interpretive considerations warrant further clarification.
Fields of Study & Subjects
Bacterial Identification and Susceptibility Testing
Sepsis Diagnosis and Treatment
Antibiotic Use and Resistance
Publication details
- Journal / source
- Journal of the American College of Emergency Physicians Open
- Volume
- 7
- Issue
- 2
- Pages
- 100319–100319
- Publication date
- 13 January 2026
- Language
- EN