Preventing Carotid Blowout: Planned Carotid Sacrifice and Cerebral Revascularization Enabling Second Reirradiation in Recurrent Nasopharyngeal Carcinoma

Advances in Radiation Oncology 2026 Open access

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Authors: Norihisa Masai, Hideya Yamazaki, Takeo Nishida, Koji Masui, Masahiko Koizumi, Daisaku Tatsumi, Taku Yasumoto, Ryoong‐Jin Oh
DOI: 10.1016/j.adro.2026.102021
Cited by: 0
References: 21

Abstract

Local recurrence of head and neck cancer after radiotherapy remains a major therapeutic challenge1. Salvage surgery or chemotherapy are standard options but often limited by anatomy or patient condition, leaving re-irradiation as the only feasible choice in selected cases2. However, re-irradiation carries a substantial risk of carotid blowout syndrome (CBOS), occurring in fewer than 10% of cases but fatal in more than half3-5. Accurate prediction and prevention of CBOS are crucial.

Fields of Study & Subjects

Head and Neck Cancer Studies Head and Neck Surgical Oncology Advanced Radiotherapy Techniques

Publication details

Journal / source
Advances in Radiation Oncology
Volume
11
Issue
7
Pages
102021–102021
Publication date
26 February 2026
Language
EN