Magnetic Resonance Guided Radiation Therapy for High-Grade Glioma in Pregnancy: Planning, Validation, and Adaptive Fetal Dose Monitoring

Advances in Radiation Oncology 2026 Open access

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Authors: Nikhil Mathews, Andrew Jaffe, Kevin McMichael, Navid Redjal, Elyce H. Cardonick, Todd A. Swanson, Stephen F. Kry, Michael E. Salacz, Justin M. Mann
DOI: 10.1016/j.adro.2026.102099
Cited by: 1
References: 8

Abstract

Introduction Managing high-grade gliomas during pregnancy requires balancing maternal oncologic control with fetal safety. While radiation therapy (RT) is essential for adjuvant treatment, it carries dose-dependent risks of teratogenicity and fetal demise. Current multidisciplinary guidelines recommend keeping cumulative fetal doses as low as reasonably achievable (ALARA), ideally

Fields of Study & Subjects

Fetal and Pediatric Neurological Disorders Cancer Risks and Factors MRI in cancer diagnosis

Publication details

Journal / source
Advances in Radiation Oncology
Publisher
Elsevier BV
Volume
11
Issue
10
Pages
102099–102099
Publication date
22 May 2026
Language
EN