Extracorporeal circuit temperature gradient and hemodynamic instability during continuous renal replacement therapy: an observational study

Annals of Intensive Care 2026 Open access

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Authors: Lorna Fraire, Téo Keraron, Matthieu Chivot, Hodane Yonis, G Chazot, Mehdi Mezidi, Louis Chauvelot, Guillaume Deniel, Jean-Christophe Richard, Laurent Bitker
DOI: 10.1016/j.aicoj.2026.100108
Cited by: 1
References: 30

Abstract

Introduction Lowering extracorporeal circuit temperature (T° CRRT ) below core temperature (T° CORE ) during continuous renal replacement therapy (CRRT) may modify hemodynamic instability (HIRRT) risk by affecting cardiac output (CO) and vasomotor tone. This study aimed to identify the mediators involved in the relationship between CRRT-to-core temperature gradient and HIRRT risk. Methods This ancillary analysis of a prospective, single-center center study (NCT03139123) included patients with stage 3 acute kidney injury, receiving CRRT for

Fields of Study & Subjects

Acute Kidney Injury Research Hemodynamic Monitoring and Therapy Abdominal Surgery and Complications

Publication details

Journal / source
Annals of Intensive Care
Publisher
Elsevier BV
Volume
16
Pages
100108–100108
Publication date
1 January 2026
Language
EN