A contemporary overview of severe community-acquired bacterial infections in pediatric intensive care units

Annals of Intensive Care 2026 Open access

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Authors: Michael Levy, Annelise Mary, Fleur Cour Andlauer, Jeremie Rousseaux, Lionel Berthomieu, Camille Bréhin, Stéphane Béchet, Montserrat Sierra-Colomina, Camille Aupiais, François Angoulvant, Elise Launay, Damien Dubois
+88 more Robert Cohen, Stéphane Leteurtre, Julien Baleine, Laurent Balu, Simon Barreault, Clémence Beauruelle, Emma Becuwe Gosselin, Matthieu Bendavid, Xavier Beretta Piccoli, Lionel Berthomieu, Stéphane Blanot, Stéphane Bonacorsi, Yvonnick Boué, Noël Boussard, Gérald Boussicault, Camille Bréhin, Alexandre Bretonneau, Arthur Charazac, Camille Chavy, Maryline Chomton Cailliez, Benoît Colomb, Fleur Cour Andlauer, Julie Cremninter, Etienne Darieux, Stéphane Dauger, Alexandra David, Sandrine De Sampaio, Damien Dubois, Audrey Dupont, Jean Duval Destin, Aben Essid, Marion Favre, Fiona Bensoussan, Ghida Ghostine, Lucie Gibold, Marie‐Laure Girardin, Chloe Hild, Sylvia Iacobelli, Charlotte Idier, Christophe Isnard, Benoit Jaulhac, Katy Jeannot, Julien Jegard, Mikaël Jokic, Aurélie Labarre, Elise Launay, Cécile Le Brun, Michael Levy, Alain Lozniewski, Annelise Mary, Fabrice Michel, Christophe Milési, Julie Missaire, Guillaume Mortamet, Simon Mounier, Audrey Mowendabeka, J. Naudin, Anouk Navion, Mehdi Oualha, Naïm Ouldali, Bruno Ozanne, Carla Parada-Rodrigues, Manon Passard, Quentin Pledran, Amandine Prenant, Pauline Ragon, Jérôme Rambaud, Sophie Reissier, Chloé Ribet, Claire Richarme, Barbara Ros, Jean‐Michel Roué, Nicolas Roullet-Renoleau, Jeremie Rousseaux, Montserrat Sierra Colomina, Laurence Tabone, Muhamed‐Kheir Taha, Asmaa Tazi, Aurore Thollot, Nicolas Traversier, Anne Tristan, Lucile Tzaroukian, Noémie Vanel, Diane Vareilles, Emmanuelle Varon, Laurent Villeneuve, Evelyne Werner, Arnaud WIEDEMANN
DOI: 10.1016/j.aicoj.2026.100112
Cited by: 1
References: 27

Abstract

Background: Community-acquired bacterial infections (CABIs) remain a leading cause of pediatric morbidity and mortality. This study aimed to provide a contemporary description of pediatric CABIs requiring admission to pediatric intensive care units (PICUs) in France. Methods: The CAPRICE study is a prospective, multicenter cohort including all children with suspected CABIs who were admitted to 28 French PICUs from January to December 2024. Demographic, clinical, microbiologic, and outcome data were prospectively collected. The primary outcome was mortality at day 28 and secondary outcomes included sequelae at day 28, PICU length of stay, and total hospital stay. Independent predictors of mortality were identified by multivariable logistic regression. Results: infection. Sequelae occurred in 15% of survivors. Conclusions: . Mortality and morbidity of these infections remain substantial.

Fields of Study & Subjects

Nosocomial Infections in ICU Neonatal and Maternal Infections Sepsis Diagnosis and Treatment

Publication details

Journal / source
Annals of Intensive Care
Publisher
Elsevier BV
Volume
16
Pages
100112–100112
Publication date
1 January 2026
Language
EN