Beyond catheter presence: Risk factors for progression to bloodstream infection during the COVID-19 era—A matched case-control study

American Journal of Infection Control 2026 Open access

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Authors: Alessandra Gomes Chauvin, André Luís Franco Cotia, Isabella Lemos Rosmino, Alexandra do Rosário Toniolo, Anderson Paulo Scorsato, Michael B. Edmond, Silvana Maria de Almeida, Alexandre R. Marra
DOI: 10.1016/j.ajic.2026.07.003
Cited by: 1
References: 7

Abstract

This matched case-control study evaluated 318 hospitalized patients with central venous catheters between 2018 and 2022 to identify risk factors for central line-associated bloodstream infection. Independent risk factors included immunosuppression, longer catheter dwell time, and prolonged hospitalization. Klebsiella pneumoniae predominated among isolates, and the pandemic period was associated with increased carbapenem and quinolone resistance, highlighting the need for sustained infection prevention and antimicrobial stewardship strategies.

Fields of Study & Subjects

Central Venous Catheters and Hemodialysis COVID-19 and healthcare impacts COVID-19 Clinical Research Studies

Publication details

Journal / source
American Journal of Infection Control
Publisher
Elsevier BV
Volume
54
Issue
11
Pages
1234-1236
Publication date
1 July 2026
Language
EN