Summary of Japanese clinical practice guidelines 2025 for the management of olfactory dysfunction

The aim of the 'Summary of Japanese Clinical Practice Guidelines 2025 for the Management of Olfactory Dysfunction' is to review the latest evidence regarding olfactory dysfunction and to present the current standard approaches for diagnosis and treatment. For the present guidelines, the Clinical Practice Guideline Committee, which is composed of otorhinolaryngologists, neurologists and oncologists with extensive experience treating patients with olfactory dysfunction, was formed by the Japanese Rhinologic Society. The Committee revised and updated the 'Clinical Practice Guidelines for the Management of Olfactory Dysfunction 2019 Edition'. Following a public comment period, the guidelines underwent external evaluation through peer review by the Scientific Committee of the Japanese Society of Otorhinolaryngology-Head and Neck Surgery. A total of 16 clinical questions consisting of three categories (diagnosis, treatment, and neurodegenerative diseases associated with dementia), are comprehensively described. These evidence-based recommendations were compiled with the consensus of the Guideline Committee.