Potent in vitro antiviral activity of 4′-Fluorouridine against diverse orthohantaviruses including Andes virus

Antiviral Research 2026 Open access

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Authors: Punya Shrivastava-Ranjan, Laura K. McMullan, Shannon L. M. Whitmer, Shilpi Jain, Payel Chatterjee, Michael K. Lo, Joel M. Montgomery, César G. Albariño, Mike Flint, Christina F. Spiropoulou
DOI: 10.1016/j.antiviral.2026.106467
Cited by: 1
References: 18

Abstract

values uniformly in the low-to sub-micromolar range. Collectively, these findings establish 4'-fluorouridine as a highly potent, pan-hantavirus inhibitor and a promising candidate for further preclinical development.

Fields of Study & Subjects

Viral Infections and Vectors Mosquito-borne diseases and control Public Health and Environmental Issues

Publication details

Journal / source
Antiviral Research
Publisher
Elsevier BV
Volume
252
Pages
106467–106467
Publication date
18 June 2026
Language
EN