Statin-associated symptoms and statin intolerance in children with familial hypercholesterolemia: Insights from 15 years of clinical practice

Atherosclerosis 2026 Open access

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Authors: Sibbeliene E. van den Bosch, Fianna C. Kowsoleea, Willemijn E. Corpeleijn, Sophie A. Huisman, Astra I.E. Kowsoleea, Albert Wiegman, B A Hutten
DOI: 10.1016/j.atherosclerosis.2026.120659
Cited by: 1
References: 16

Abstract

BACKGROUND AND AIMS: To reduce the increased premature cardiovascular risk in children with heterozygous familial hypercholesterolemia (FH), statins are the first pharmacological step. This study aims to assess the incidence of statin-associated symptoms (SAS) and statin intolerance in pediatric FH patients. METHODS: Children (

Fields of Study & Subjects

Lipoproteins and Cardiovascular Health Lipid metabolism and disorders Cholesterol and Lipid Metabolism

Publication details

Journal / source
Atherosclerosis
Publisher
Elsevier BV
Volume
414
Pages
120659–120659
Publication date
4 February 2026
Language
EN