Mediastinal Mature Teratoma With Malignant Transformation to Colorectal-Type Adenocarcinoma

Annals of Thoracic Surgery Short Reports 2026 Open access

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Authors: Amber T. Vinluan, Erik Schwarze, Michael G. Bayerl, Erik J. Rupard, Pauline H. Go
DOI: 10.1016/j.atssr.2025.12.019
Cited by: 0
References: 8

Abstract

Mature teratomas represent 5% to 10% of all mediastinal tumors, and malignant transformation is exceedingly rare. A 51-year-old man with newly diagnosed prostate cancer was incidentally found to have an anterior mediastinal mass suggestive of a teratoma on staging workup. Robotic thymectomy was performed, revealing a mature teratoma with malignant transformation to colorectal-type adenocarcinoma. Circulating tumor DNA was negative for measurable residual disease. The patient was managed with surveillance, including serial imaging and tumor markers.

Fields of Study & Subjects

Testicular diseases and treatments Teratomas and Epidermoid Cysts Cardiac tumors and thrombi

Publication details

Journal / source
Annals of Thoracic Surgery Short Reports
Volume
4
Issue
2
Pages
516–520
Publication date
13 January 2026
Language
EN