Computational modeling and optimization of scFv-based receptors to support CAR-T design targeting CD19 for enhanced binding robustness and reduced off-target propensity

Biochemical and Biophysical Research Communications 2026

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Authors: Kadalmani Krishnan, Anita Chugh, Ravikrishnan Rajaram, Anagha Shamsundar Setlur, Chandrashekar Karunakaran, Akshay Uttarkar, Vidya Niranjan
DOI: 10.1016/j.bbrc.2026.153464
Cited by: 1
References: 31

Fields of Study & Subjects

CAR-T cell therapy research Monoclonal and Polyclonal Antibodies Research vaccines and immunoinformatics approaches

Publication details

Journal / source
Biochemical and Biophysical Research Communications
Publisher
Elsevier BV
Volume
811
Pages
153464–153464
Publication date
13 February 2026
Language
EN